منابع مشابه
Obesity and type 2 diabetes
Obesity and type 2 diabetes (T2DM) are public health problems, with health consequences and economic costs that have raised concern worldwide. The increase in the prevalence of diabetes parallels that of obesity. Some experts call this dual epidemic “diabesity”. Elevated body mass index (BMI) and waist circumference (WC) were significantly associated T2DM. One consequence of obesity is an incre...
متن کاملInflammation and type one diabetes.
Type one diabetes (T1D) is a complex T cell-mediated autoimmune disease, the defining feature of which is the destruction of the insulin-secreting beta- (β)- cell. Both genetic and environmental factors combine to precipitate disease, and the outcome of the pathological process is dependent on multiple inter-related factors. In this review, the mechanisms behind the initiation and propagation o...
متن کاملCommon Variations in Perilipin rs1052700 and FTO rs3751812 Genes, Central Obesity, and Risk Type-2 Diabetes
Background: Perilipins are proteins at the external level of the lipid glob in adipocytes steroid-generating cells and play a central role in lipid storage and breakdown. FTO gene is associated with Type-2 diabetes (T2D) and increased fat mass. Association of Perilipin and FTO genes polymorphism with T2D was investigated. Methods: Clinical traits in a random sample of 183 Iranian men and wom...
متن کاملSerum Adiponectin and Vaspin levels in Abdominal Obesity and Type 2 Diabetes Mellitus
Abstract Objective: Adiponectin and vaspin are adipocyte-derived proteins and involved in the regulation of glucose metabolism and obesity related disorders. The mechanisms that adipokines might be linked to disturbance of glucose are unclear. Thus, this study investigated the levels of serum adiponectin and vaspin, blood lipid profiles, and abdominal obesity in type 2 diabetes (T2DM) patients...
متن کاملSerum resistin a biomarker of type II diabetes development
Background: Resistin and ghrelin are hormones that have roles in the glucose and lipid homeostasis and weight regulation. Human studies regarding resistin and ghrelin in diabetic patients are scarce, especially in the cases of normotensive and non-obese patients. This study was designed to illuminate some of the missing points.Methods: Eighty diabetic patients and eighty healthy individuals par...
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ژورنال
عنوان ژورنال: International Journal of Obesity
سال: 2003
ISSN: 0307-0565,1476-5497
DOI: 10.1038/sj.ijo.0802490